Select Publications
Clinical Genomic Diagnostics
Wu C, Devkota B, et al., “Rapid and accurate interpretation of clinical exomes using Phenoxome: a computational phenotype-driven approach”, European Journal of Human Genetics, 2019. Read more
Wu C, Zhao X, et al., “Using machine learning to identify true somatic variants from next-generation sequencing”, Clinical Chemistry, 2019. Read more
Evans P, Wu C, et al., “Genetic variant pathogenicity prediction trained using disease specific clinical sequencing datasets”, Genome Research, 2019. Read more
Gibson K, Nesbitt A, (et al. including Wu C), “Novel findings with re-assessment of exome data: implications for validation testing and interpretation of genomic data”, Genetics in Medicine, 2017. Read more
Non-coding RNAs
Wu C, Zhao X, Clark P, “Computational methods for microRNA and PIWI-interacting RNA gene discovery and functional predictions”, AGO-driven Non-Coding RNAs, 35-53, 2019. Read more
Wu C, Bardes E, Jegga A and Aronow B, “ToppMir: an analysis workbench for ranking functionally significant miRs and mRNA targets based on biological associations”, Nucleic Acids Research, 2014. Read more
Disease Gene Identification & Gene Regulation
Zhu C, Wu C, Aronow B and Jegga A, “Computational approaches for human disease gene prediction and ranking”, Systems Analysis of Human Multigene Disorders, 69-84, 2014. Read more
Wu C, Zhu C and Jegga A, “Integrative literature and data mining to rank disease candidate genes”, Biomedical Literature Mining, 207-226, 2014.
Wu C, Bakshi A, Aronow B, Jegga A and Bhatnagar R, “A biclustering algorithm to discover functional modules from ENCODE ChIP-Seq data”, 13th IEEE ICDMW, 2014. Read more
Drug Repurposing
Wu C, Gudivada R, Aronow B and Jegga A, “Computational drug repositioning through heterogeneous network clustering”, BMC Systems Biology, 7(5), 2013. Read more
Zhu C, Wu C and Jegga A, “Network biology methods for drug repositioning”, Post-genom. Approaches Drug Vaccine Dev, 2015.